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Retrograde Shiga Toxin Trafficking Is Regulated by ARHGAP21 and Cdc42

Shiga-toxin–producing Escherichia coli remain a food-borne health threat. Shiga toxin is endocytosed by intestinal epithelial cells and transported retrogradely through the secretory pathway. It is ultimately translocated to the cytosol where it inhibits protein translation. We found that Shiga toxi...

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Detalhes bibliográficos
Main Authors: Hehnly, Heidi, Longhini, Katrina Marie, Chen, Ji-Long, Stamnes, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762141/
https://ncbi.nlm.nih.gov/pubmed/19692570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-02-0155
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