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Retrograde Shiga Toxin Trafficking Is Regulated by ARHGAP21 and Cdc42

Shiga-toxin–producing Escherichia coli remain a food-borne health threat. Shiga toxin is endocytosed by intestinal epithelial cells and transported retrogradely through the secretory pathway. It is ultimately translocated to the cytosol where it inhibits protein translation. We found that Shiga toxi...

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Bibliografiset tiedot
Päätekijät: Hehnly, Heidi, Longhini, Katrina Marie, Chen, Ji-Long, Stamnes, Mark
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2009
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762141/
https://ncbi.nlm.nih.gov/pubmed/19692570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-02-0155
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