BRD4 inhibitor IBET upregulates p27kip/cip protein stability in neuroendocrine tumor cells

The prevalence of neuroendocrine tumors (NETs) has recently been increasing. Although various drugs such as Octreotide and its analogs show certain efficacy, NETs in many patients progress and metastasize. It is desirable to develop new interventions to improve the therapy. Here we show that human n...

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Publicat a:Cancer Biol Ther
Autors principals: Wang, Lei, Matkar, Smita, Xie, Gengchen, An, Chiying, He, Xin, Kong, Xiangchen, Liu, Xiuheng, Hua, Xianxin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450742/
https://ncbi.nlm.nih.gov/pubmed/28281917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1294291
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