BRD4 inhibitor IBET upregulates p27kip/cip protein stability in neuroendocrine tumor cells

The prevalence of neuroendocrine tumors (NETs) has recently been increasing. Although various drugs such as Octreotide and its analogs show certain efficacy, NETs in many patients progress and metastasize. It is desirable to develop new interventions to improve the therapy. Here we show that human n...

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Dettagli Bibliografici
Pubblicato in:Cancer Biol Ther
Autori principali: Wang, Lei, Matkar, Smita, Xie, Gengchen, An, Chiying, He, Xin, Kong, Xiangchen, Liu, Xiuheng, Hua, Xianxin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450742/
https://ncbi.nlm.nih.gov/pubmed/28281917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1294291
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