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Non-canonical activity of the podosomal formin FMNL1γ supports immune cell migration
Having previously located the formin FMNL1 in macrophage podosomes, we developed an in vivo model to assess the role of FMNL1 in the migration activities of primary macrophages. Deletion of FMNL1 in mice was genetically lethal; however, targeted deletion in macrophages was achieved by employing macr...
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| Veröffentlicht in: | J Cell Sci |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5450187/ https://ncbi.nlm.nih.gov/pubmed/28348104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.195099 |
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