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Non-canonical activity of the podosomal formin FMNL1γ supports immune cell migration

Having previously located the formin FMNL1 in macrophage podosomes, we developed an in vivo model to assess the role of FMNL1 in the migration activities of primary macrophages. Deletion of FMNL1 in mice was genetically lethal; however, targeted deletion in macrophages was achieved by employing macr...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Miller, Matthew R., Miller, Eric W., Blystone, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450187/
https://ncbi.nlm.nih.gov/pubmed/28348104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.195099
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