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Long-term clinical outcomes following treatment with alpha 1-proteinase inhibitor for COPD associated with alpha-1 antitrypsin deficiency: a look at the evidence
Alpha-1 antitrypsin deficiency (AATD) is a common hereditary disorder caused by mutations in the SERPINA1 gene, which encodes alpha-1 antitrypsin (AAT; also known as alpha 1-proteinase inhibitor, A(1)-PI). An important function of A(1)-PI in the lung is to inhibit neutrophil elastase, one of various...
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| Pubblicato in: | Respir Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5450185/ https://ncbi.nlm.nih.gov/pubmed/28558837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0574-1 |
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