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Long-term clinical outcomes following treatment with alpha 1-proteinase inhibitor for COPD associated with alpha-1 antitrypsin deficiency: a look at the evidence

Alpha-1 antitrypsin deficiency (AATD) is a common hereditary disorder caused by mutations in the SERPINA1 gene, which encodes alpha-1 antitrypsin (AAT; also known as alpha 1-proteinase inhibitor, A(1)-PI). An important function of A(1)-PI in the lung is to inhibit neutrophil elastase, one of various...

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Publicat a:Respir Res
Autors principals: Rahaghi, Franck F., Miravitlles, Marc
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450185/
https://ncbi.nlm.nih.gov/pubmed/28558837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0574-1
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