HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference

BACKGROUND: Sexual difference has been shown in the pathogenesis of chronic kidney disease induced by hypertension. Females are protected from hypertension and related end-organ damage. Augmentation of renal proximal tubular angiotensinogen (AGT) expression can promote intrarenal angiotensin formati...

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Publicat a:Biol Sex Differ
Autors principals: Bourgeois, Camille T., Satou, Ryousuke, Prieto, Minolfa C.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450130/
https://ncbi.nlm.nih.gov/pubmed/28572913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-017-0140-z
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