Encapsulation of 16-Hydroxycleroda-3,13-Dine-16,15-Olide in Mesoporous Silica Nanoparticles as a Natural Dipeptidyl Peptidase-4 Inhibitor Potentiated Hypoglycemia in Diabetic Mice

Natural supplements comprise good efficacy with less adverse effects as against diabetic therapy, but their advancement as anti-diabetic agents is unsatisfactory with regard to the delivery system. Dipeptidyl peptidase-4 (DPP4)/CD26) can degrade glucagon-like pepetide-1 (GLP-1) which renders a decre...

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Publicat a:Nanomaterials (Basel)
Autors principals: Huang, Po-Kai, Lin, Shi-Xiang, Tsai, May-Jywan, Leong, Max K., Lin, Shian-Ren, Kankala, Ranjith Kumar, Lee, Chia-Hung, Weng, Ching-Feng
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449993/
https://ncbi.nlm.nih.gov/pubmed/28498352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano7050112
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