16α-Hydroxycleroda-3,13 (14)Z-dien-15,16-olide from Polyalthia longifolia: a safe and orally active antileishmanial agent

BACKGROUND AND PURPOSE: New antileishmanials from natural products are urgently needed due to the emergence of drug resistance complicated by severe cytotoxic effects. 16α-Hydroxycleroda-3,13 (14)Z-dien-15,16-olide (Compound 1) from Polyalthia longifolia was found to be a potential antileishmanial a...

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Detalhes bibliográficos
Main Authors: Misra, Pragya, Sashidhara, Koneni V, Singh, Suriya Pratap, Kumar, Awanish, Gupta, Reema, Chaudhaery, Shailendra S, Gupta, Souvik Sen, Majumder, HK, Saxena, Anil K, Dube, Anuradha
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839272/
https://ncbi.nlm.nih.gov/pubmed/20136832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00609.x
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