Gene Electrotransfer of Plasmid-Encoding IL-12 Recruits the M1 Macrophages and Antigen-Presenting Cells Inducing the Eradication of Aggressive B16F10 Murine Melanoma

Cancer immunotherapy is currently one of the leading approaches in cancer treatment. Gene electrotransfer of plasmids encoding interleukin 12 (IL-12) into the cells leads to the production of IL-12, which drives immune cell polarization to an antitumoral response. One of the cell types that shows gr...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Lampreht Tratar, Ursa, Loiacono, Luisa, Cemazar, Maja, Kamensek, Urska, Fazio, Vito Michele, Sersa, Gregor, Signori, Emanuela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449735/
https://ncbi.nlm.nih.gov/pubmed/28596641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5285890
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