Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer

Electroporation is a platform technology for drug and gene delivery. When applied to cell in vitro or tissues in vivo, it leads to an increase in membrane permeability for molecules which otherwise cannot enter the cell (e.g., siRNA, plasmid DNA, and some chemotherapeutic drugs). The therapeutic eff...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Immunother
Main Authors: Sersa, Gregor, Teissie, Justin, Cemazar, Maja, Signori, Emanuela, Kamensek, Urska, Marshall, Guillermo, Miklavcic, Damijan
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
Fag:
Focussed Research Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554735/
https://ncbi.nlm.nih.gov/pubmed/26067277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1724-2
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