Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells

An aberrant oxygen environment at birth increases the severity of respiratory viral infections later in life through poorly understood mechanisms. Here, we show that alveolar epithelial cell (AEC) 2 cells (AEC2s), progenitors for AEC1 cells, are depleted in adult mice exposed to neonatal hypoxia or...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Yee, Min, Domm, William, Gelein, Robert, Bentley, Karen L. de Mesy, Kottmann, R. Matthew, Sime, Patricia J., Lawrence, B. Paige, O’Reilly, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449509/
https://ncbi.nlm.nih.gov/pubmed/27967234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0150OC
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