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Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling

Alveolar epithelial type II (ATII) cells are essential for maintaining normal lung homeostasis because they produce surfactant, express innate immune proteins, and can function as progenitors for alveolar epithelial type I (ATI) cells. Although autocrine production of transforming growth factor (TGF...

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Autori principali: Zhao, Lan, Yee, Min, O'Reilly, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763037/
https://ncbi.nlm.nih.gov/pubmed/23831617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00032.2013
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