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In silico analyses of deleterious missense SNPs of human apolipoprotein E3

ApoE3 is the major chylomicron apolipoprotein, binding in a specific liver peripheral cell receptor, allowing transport and normal catabolism of triglyceride-rich lipoprotein constituents. Point mutations in ApoE3 have been associated with Alzheimer’s disease, type III hyperlipoproteinemia, atherosc...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Pires, Allan S., Porto, William F., Franco, Octavio L., Alencar, Sérgio A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449402/
https://ncbi.nlm.nih.gov/pubmed/28559539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01737-w
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