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Deconstructing the germinal center, one cell at a time
Successful vaccination relies on driving the immune response towards high specificity, affinity and longevity. Germinal centers facilitate the evolution of antigen-specific B cells by iterative rounds of diversification, selection, and differentiation to memory and plasma cells. Experimental evidenc...
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Publicado no: | Curr Opin Immunol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5449228/ https://ncbi.nlm.nih.gov/pubmed/28319730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2017.03.007 |
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