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Treatment of TNF-Tg Mice with Anti-TNF Restores Lymphatic Contraction, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress

BACKGROUND: Recent studies have demonstrated that there is an inverse relationship between lymphatic egress and inflammatory arthritis in affected joints. As a model, TNF-transgenic (TNF-Tg) mice develop advanced arthritis following draining lymph node collapse, and loss of lymphatic contractions do...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Bouta, Echoe M., Kuzin, Igor, de Mesy Bentley, Karen, Wood, Ronald W., Rahimi, Homaira, Ji, Rui-Cheng, Ritchlin, Christopher T., Bottaro, Andrea, Xing, Lianping, Schwarz, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449211/
https://ncbi.nlm.nih.gov/pubmed/28118521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40047
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