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Efficacy of B cell Depletion Therapy on Joint Flare is Associated with Increased Lymphatic Flow

OBJECTIVE: B cell depletion therapy (BCDT) ameliorates rheumatoid arthritis by mechanisms that are incompletely understood. Arthritic flare in tumor necrosis factor transgenic (TNF-Tg) mice is associated with efferent lymph node (LN) “collapse,” triggered by B cell translocation into lymphatic space...

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Autors principals: Li, Jie, Ju, Yawen, Bouta, Echoe M., Xing, Lianping, Wood, Ronald W., Kuzin, Igor, Bottaro, Andrea, Ritchlin, Christopher T., Schwarz, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535508/
https://ncbi.nlm.nih.gov/pubmed/23002006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37709
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