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Lipid-mediated, reversible misfolding of a sterol-sensing domain protein

Cellular quality control requires recognition of common features of misfolding, and so is not typically associated with the specific targeting of individual proteins. However, physiologically regulated degradation of yeast HMG-CoA reductase (Hmg2p) occurs by the HRD endoplasmic reticulum quality con...

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Detalles Bibliográficos
Main Authors: Shearer, Alexander G, Hampton, Randolph Y
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2005
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC544911/
https://ncbi.nlm.nih.gov/pubmed/15635451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600498
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