Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model

Iron oxide nanoparticles (IONPs) are promising nanomaterials for biomedical applications. However, their inflammatory potential has not been fully established. Here, we used a lepirudin anti-coagulated human whole blood model to evaluate the potential of 10 nm IONPs to activate the complement system...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Wolf-Grosse, Susann, Rokstad, Anne Mari, Ali, Syed, Lambris, John D, Mollnes, Tom E, Nilsen, Asbjørn M, Stenvik, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449102/
https://ncbi.nlm.nih.gov/pubmed/28579778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S136453
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