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Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a (64)Cu-Labeled Monoclonal Antibody, MAb159

Overexpression of the GRP78 receptor on cell surfaces has been linked with tumor growth, metastasis, and resistance to therapy. We developed a (64)Cu-labeled probe for PET imaging of tumor GRP78 expression based on a novel anti-GRP78 monoclonal antibody, MAb159. METHODS: MAb159 was conjugated with t...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Wang, Hui, Li, Dan, Liu, Shuanglong, Liu, Ren, Yuan, Hong, Krasnoperov, Valery, Shan, Hong, Conti, Peter S., Gill, Parkash S., Li, Zibo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448786/
https://ncbi.nlm.nih.gov/pubmed/25908833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.155812
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