Design, Synthesis, and Validation of Axl-Targeted Monoclonal Antibody Probe for microPET Imaging in Human Lung Cancer Xenograft

[Image: see text] Accumulating experimental evidence indicates that overexpression of the oncogenic receptor tyrosine kinase, Axl, plays a key role in the tumorigenesis and metastasis of various types of cancer. The objective of this study is to design a novel imaging probe based on the monoclonal a...

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Bibliografiska uppgifter
I publikationen:Mol Pharm
Huvudupphovsmän: Liu, Shuanglong, Li, Dan, Guo, Jiacong, Canale, Nicolette, Li, Xiuqing, Liu, Ren, Krasnoperov, Valery, Gill, Parkash S., Conti, Peter S., Shan, Hong, Li, Zibo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224514/
https://ncbi.nlm.nih.gov/pubmed/24978094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500307t
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