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Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope protein.

A nonglycosylated denatured form of human immunodeficiency virus (HIV) 1 glycoprotein gp120 (Env 2-3), which does not bind to CD4, was used with muramyl tripeptide as adjuvant to immunize HIV-seronegative healthy volunteers. In all the volunteers, three 50-micrograms injections of Env 2-3 induced pr...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Abrignani, S, Montagna, D, Jeannet, M, Wintsch, J, Haigwood, N L, Shuster, J R, Steimer, K S, Cruchaud, A, Staehelin, T
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54487/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1696717/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6136
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