Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope protein.

A nonglycosylated denatured form of human immunodeficiency virus (HIV) 1 glycoprotein gp120 (Env 2-3), which does not bind to CD4, was used with muramyl tripeptide as adjuvant to immunize HIV-seronegative healthy volunteers. In all the volunteers, three 50-micrograms injections of Env 2-3 induced pr...

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Detalhes bibliográficos
Main Authors: Abrignani, S, Montagna, D, Jeannet, M, Wintsch, J, Haigwood, N L, Shuster, J R, Steimer, K S, Cruchaud, A, Staehelin, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54487/
https://ncbi.nlm.nih.gov/pubmed/1696717
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