Development of antiproliferative long-circulating liposomes co-encapsulating doxorubicin and curcumin, through the use of a quality-by-design approach

The aim of this work was to use the quality-by-design (QbD) approach in the development of long-circulating liposomes co-loaded with curcumin (CUR) and doxorubicin (DOX) and to evaluate the cytotoxic potential of these liposomes in vitro using C26 murine colon carcinoma cell line. Based on a risk as...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Tefas, Lucia Ruxandra, Sylvester, Bianca, Tomuta, Ioan, Sesarman, Alina, Licarete, Emilia, Banciu, Manuela, Porfire, Alina
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448697/
https://ncbi.nlm.nih.gov/pubmed/28579758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S129008
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