Folic Acid Modulates Matrix Metalloproteinase-2 Expression, Alleviates Neuropathic Pain, and Improves Functional Recovery in Spinal Cord-Injured Rats

BACKGROUND: The molecular underpinnings of spinal cord injury (SCI) associated with neuropathic pain (NP) are unknown. Recent studies have demonstrated that matrix metalloproteinases (MMPs) such as MMP2 play a critical role in inducing NP following SCI. Promoter methylation of MMPs is known to suppr...

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Publicado en:Ann Neurosci
Main Authors: Miranpuri, Gurwattan S., Meethal, Sivan Vadakkadath, Sampene, Emmanuel, Chopra, Abhishek, Buttar, Seah, Nacht, Carrie, Moreno, Neydis, Patel, Kush, Liu, Lisa, Singh, Anupama, Singh, Chandra K., Hariharan, Nithya, Iskandar, Bermans, Resnick, Daniel K.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448437/
https://ncbi.nlm.nih.gov/pubmed/28588362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000475896
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