Folic Acid Modulates Matrix Metalloproteinase-2 Expression, Alleviates Neuropathic Pain, and Improves Functional Recovery in Spinal Cord-Injured Rats

BACKGROUND: The molecular underpinnings of spinal cord injury (SCI) associated with neuropathic pain (NP) are unknown. Recent studies have demonstrated that matrix metalloproteinases (MMPs) such as MMP2 play a critical role in inducing NP following SCI. Promoter methylation of MMPs is known to suppr...

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發表在:Ann Neurosci
Main Authors: Miranpuri, Gurwattan S., Meethal, Sivan Vadakkadath, Sampene, Emmanuel, Chopra, Abhishek, Buttar, Seah, Nacht, Carrie, Moreno, Neydis, Patel, Kush, Liu, Lisa, Singh, Anupama, Singh, Chandra K., Hariharan, Nithya, Iskandar, Bermans, Resnick, Daniel K.
格式: Artigo
語言:Inglês
出版: S. Karger AG 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448437/
https://ncbi.nlm.nih.gov/pubmed/28588362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000475896
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