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A Novel Approach on Drug Delivery: Investigation of A New Nano-Formulation of Liposomal Doxorubicin and Biological Evaluation of Entrapped Doxorubicin on Various Osteosarcoma Cell Lines

OBJECTIVE: In this study we prepared a novel formulation of liposomal doxorubicin (L- DOX). The drug dose was optimized by analyses of cellular uptake and cell viability of osteosarcoma (OS) cell lines upon exposure to nanoliposomes that contained varying DOX concentrations. We intended to reduce th...

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Bibliographic Details
Published in:Cell J
Main Authors: Haghiralsadat, Fateme, Amoabediny, Ghasem, Sheikhha, Mohammad Hasan, Forouzanfar, Tymour, Helder, Marco N., Zandieh-doulabi, Behrouz
Format: Artigo
Language:Inglês
Published: Royan Institute 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448319/
https://ncbi.nlm.nih.gov/pubmed/28580308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2017.4502
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