Maturation arrest in early postnatal sensory receptors by deletion of the miR-183/96/182 cluster in mouse

The polycistronic miR-183/96/182 cluster is preferentially and abundantly expressed in terminally differentiating sensory epithelia. To clarify its roles in the terminal differentiation of sensory receptors in vivo, we deleted the entire gene cluster in mouse germline through homologous recombinatio...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Fan, Jianguo, Jia, Li, Li, Yan, Ebrahim, Seham, May-Simera, Helen, Wood, Alynda, Morell, Robert J., Liu, Pinghu, Lei, Jingqi, Kachar, Bechara, Belluscio, Leonardo, Qian, Haohua, Li, Tiansen, Li, Wei, Wistow, Graeme, Dong, Lijin
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448201/
https://ncbi.nlm.nih.gov/pubmed/28484004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619442114
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