Injectable nanofibrous spongy microspheres for NR4A1 plasmid DNA transfection to reverse fibrotic degeneration and support disc regeneration

Safe and efficient gene therapy is highly desired for controlling pathogenic fibrosis of nucleus pulposus (NP) tissue, which would result in intervertebral disc (IVD) degeneration and disability if left untreated. In this work, a hyperbranched polymer (HP) with high plasmid DNA (pDNA) binding affini...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Feng, Ganjun, Zhang, Zhanpeng, Dang, Ming, Zhang, Xiaojin, Doleyres, Yasmine, Song, Yueming, Chen, Di, Ma, Peter X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448136/
https://ncbi.nlm.nih.gov/pubmed/28376367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.03.029
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados