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A genetic variant of the sperm-specific SLO3 K(+) channel has altered pH and Ca(2+) sensitivities
To fertilize an oocyte, sperm must first undergo capacitation in which the sperm plasma membrane becomes hyperpolarized via activation of potassium (K(+)) channels and resultant K(+) efflux. Sperm-specific SLO3 K(+) channels are responsible for these membrane potential changes critical for fertiliza...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448129/ https://ncbi.nlm.nih.gov/pubmed/28377504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776013 |
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