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Delineating distinct heme-scavenging and -binding functions of domains in MF6p/helminth defense molecule (HDM) proteins from parasitic flatworms

MF6p/FhHDM-1 is a small protein secreted by the parasitic flatworm (trematode) Fasciola hepatica that belongs to a broad family of heme-binding proteins (MF6p/helminth defense molecules (HDMs)). MF6p/HDMs are of interest for understanding heme homeostasis in trematodes and as potential targets for t...

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Vydáno v:J Biol Chem
Hlavní autoři: Martínez-Sernández, Victoria, Mezo, Mercedes, González-Warleta, Marta, Perteguer, María J., Gárate, Teresa, Romarís, Fernanda, Ubeira, Florencio M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448095/
https://ncbi.nlm.nih.gov/pubmed/28348084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771675
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