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Autophagy and Its Impact on Neurodegenerative Diseases: New Roles for TDP-43 and C9orf72

Autophagy is a catabolic mechanism where intracellular material is degraded by vesicular structures called autophagolysosomes. Autophagy is necessary to maintain the normal function of the central nervous system (CNS), avoiding the accumulation of misfolded and aggregated proteins. Consistently, imp...

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Bibliografiska uppgifter
I publikationen:Front Mol Neurosci
Huvudupphovsmän: Budini, Mauricio, Buratti, Emanuele, Morselli, Eugenia, Criollo, Alfredo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447761/
https://ncbi.nlm.nih.gov/pubmed/28611593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00170
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