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The Anti-Inflammatory Effects of Lipoxygenase and Cyclo-Oxygenase Inhibitors in Inflammation-Induced Human Fetal Glia Cells and the Aβ Degradation Capacity of Human Fetal Astrocytes in an Ex vivo Assay

Chronic inflammation is a common phenomenon present in the background of multiple neurodegenerative diseases, including Alzheimer's disease (AD). The arachidonic acid pathway overproduces proinflammatory eicosanoids during these states and glial cells in the brain gradually lose their vital fun...

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Publicat a:Front Neurosci
Autors principals: Pihlaja, Rea, Haaparanta-Solin, Merja, Rinne, Juha O.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447716/
https://ncbi.nlm.nih.gov/pubmed/28611577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00299
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