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RNA toxicity and foci formation in microsatellite expansion diseases
More than 30 incurable neurological and neuromuscular diseases are caused by simple microsatellite expansions consisted of 3–6 nucleotides. These repeats can occur in non-coding regions and often result in a dominantly inherited disease phenotype that is characteristic of a toxic RNA gain-of-functio...
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| 出版年: | Curr Opin Genet Dev |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5447490/ https://ncbi.nlm.nih.gov/pubmed/28208060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.01.005 |
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