Epigenetic Modifications to H3K9 in Renal Tubulointerstitial Cells after Unilateral Ureteric Obstruction and TGF-β1 Stimulation

Introduction: Epigenetic regulation of fibrogenesis through post-translational histone modifications (marks) may be a key determinant of progression in renal disease. In this study, we examined the distribution and acquisition of histone 3 Lysine 9 (H3K9) marks after injury and stimulation with the...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Hewitson, Timothy D., Holt, Stephen G., Tan, Sven-Jean, Wigg, Belinda, Samuel, Chrishan S., Smith, Edward R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447091/
https://ncbi.nlm.nih.gov/pubmed/28611663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00307
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