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The Ageing Genome, Clonal Mosaicism and Chronic Disease

Clonal mosaicism arises when a post-zygotic mutational event is detectable in subpopulations of cells as an alternative genotype while not present in the germline genome. Although described in a subset of pediatric disorders, new genomic technologies have detected higher than anticipated frequencies...

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Bibliografiska uppgifter
I publikationen:Curr Opin Genet Dev
Huvudupphovsmän: Machiela, Mitchell J., Chanock, Stephen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446794/
https://ncbi.nlm.nih.gov/pubmed/28068559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2016.12.002
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