Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

BACKGROUND: Genetic studies for complex diseases have predominantly discovered main effects at individual loci, but have not focused on genomic and environmental contexts important for a phenotype. Gene Set Enrichment Analysis (GSEA) aims to address this by identifying sets of genes or biological pa...

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Vydáno v:BioData Min
Hlavní autoři: Tragante, Vinicius, Gho, Johannes M. I. H., Felix, Janine F., Vasan, Ramachandran S., Smith, Nicholas L., Voight, Benjamin F., Palmer, Colin, van der Harst, Pim, Moore, Jason H., Asselbergs, Folkert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446754/
https://ncbi.nlm.nih.gov/pubmed/28559929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-017-0137-5
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