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A human cellular sequence implicated in trk oncogene activation is DNA damage inducible.

Xeroderma pigmentosum cells, which are deficient in the repair of UV light-induced DNA damage, have been used to clone DNA-damage-inducible transcripts in human cells. The cDNA clone designated pC-5 hybridizes on RNA gel blots to a 1-kilobase transcript, which is moderately abundant in nontreated ce...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ben-Ishai, R, Scharf, R, Sharon, R, Kapten, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1696715/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6039
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