Glucagon‐like peptide‐1 receptor signalling reduces microvascular thrombosis, nitro‐oxidative stress and platelet activation in endotoxaemic mice

BACKGROUND AND PURPOSE: Excessive inflammation in sepsis causes microvascular thrombosis and thrombocytopenia associated with organ dysfunction and high mortality. The present studies aimed to investigate whether inhibition of dipeptidyl peptidase‐4 (DPP‐4) and supplementation with glucagon‐like pep...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Steven, Sebastian, Jurk, Kerstin, Kopp, Maximilian, Kröller‐Schön, Swenja, Mikhed, Yuliya, Schwierczek, Kathrin, Roohani, Siyer, Kashani, Fatemeh, Oelze, Matthias, Klein, Thomas, Tokalov, Sergey, Danckwardt, Sven, Strand, Susanne, Wenzel, Philip, Münzel, Thomas, Daiber, Andreas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Themed Section: Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446582/
https://ncbi.nlm.nih.gov/pubmed/27435156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13549
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