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Escape of U251 glioma cells from temozolomide-induced senescence was modulated by CDK1/survivin signaling

Temozolomide (TMZ) has been widely used in conjunction with radiotherapy for treating various types of cancers. However, tumor cells arrested in senescence due to TMZ administration can sometimes escape and become drug resistant. In the current study, the possible role of survivin in the senescence...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Song, Zhenhua, Pan, Yunyun, Ling, Gengqiang, Wang, Shiyong, Huang, Min, Jiang, Xiaodan, Ke, Yiquan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446501/
https://ncbi.nlm.nih.gov/pubmed/28559969
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