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PEA3 protects against gentamicin nephrotoxicity: role of mitochondrial dysfunction

Toxin-induced nephrotoxicity is one of the major causes leading to the acute kidney injury (AKI). Among these nephrotoxic toxins, gentamicin can induce AKI with elusive mechanisms. Emerging evidence demonstrated that PEA3 (polyomavirus enhancer activator 3) contributed to the nephrogenesis, while it...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Chen, Qiuxia, Cui, Yiyun, Ding, Guixia, Jia, Zhanjun, Zhang, Yue, Zhang, Aihua, Huang, Songming
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446500/
https://ncbi.nlm.nih.gov/pubmed/28559968
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