Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management

Ultraviolet B (UVB), in addition to having carcinogenic activity, is required for the production of vitamin D3 (D3) in the skin which supplies >90% of the body's requirement. Vitamin D is activated through hydroxylation by 25-hydroxylases (CYP2R1 or CYP27A1) and 1α-hydroxylase (CYP27B1) to p...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Slominski, Andrzej T, Brożyna, Anna A, Zmijewski, Michal A, Jóźwicki, Wojciech, Jetten, Anton M, Mason, Rebecca S, Tuckey, Robert C, Elmets, Craig A
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446295/
https://ncbi.nlm.nih.gov/pubmed/28218743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2017.3
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