MicroRNA-200b is downregulated in colon cancer budding cells

BACKGROUND: The microRNA-200 (miR-200) family acts as a major suppressor of epithelial-mesenchymal transition (EMT). Impaired miR-200 expression may lead to EMT initiation and eventually cancer dissemination. The presence of tumor budding cells (TBC) is associated with metastasis and poor prognosis,...

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Publicado en:PLoS One
Autores principales: Knudsen, Kirsten Nguyen, Lindebjerg, Jan, Nielsen, Boye Schnack, Hansen, Torben Frøstrup, Sørensen, Flemming Brandt
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446202/
https://ncbi.nlm.nih.gov/pubmed/28552992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178564
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