MicroRNA-200b is downregulated in colon cancer budding cells

BACKGROUND: The microRNA-200 (miR-200) family acts as a major suppressor of epithelial-mesenchymal transition (EMT). Impaired miR-200 expression may lead to EMT initiation and eventually cancer dissemination. The presence of tumor budding cells (TBC) is associated with metastasis and poor prognosis,...

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Udgivet i:PLoS One
Main Authors: Knudsen, Kirsten Nguyen, Lindebjerg, Jan, Nielsen, Boye Schnack, Hansen, Torben Frøstrup, Sørensen, Flemming Brandt
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446202/
https://ncbi.nlm.nih.gov/pubmed/28552992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178564
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