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Gene delivery of human apolipoprotein E alters brain Aβ burden in a mouse model of Alzheimer's disease
Apolipoprotein E (apoE) alleles are important genetic risk factors for Alzheimer's disease (AD), with the ε4 allele increasing and the ε2 allele decreasing risk for developing AD. ApoE has been shown to influence brain amyloid-β peptide (Aβ) and amyloid burden, both in humans and in transgenic...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC544620/ https://ncbi.nlm.nih.gov/pubmed/15657137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409072102 |
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