Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature

Apoptosis plays a central role in developmental and pathological angiogenesis and vessel regression. Bim is a pro-apoptotic Bcl-2 family member that plays a prominent role in both developmental and pathological ocular vessel regression, and neovascularization. Endothelial cells (EC) and pericytes (P...

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Veröffentlicht in:PLoS One
Hauptverfasser: Wang, Shoujian, Zaitoun, Ismail S., Johnson, Ryan P., Jamali, Nasim, Gurel, Zafer, Wintheiser, Catherine M., Strasser, Andreas, Lindner, Volkhard, Sheibani, Nader, Sorenson, Christine M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446173/
https://ncbi.nlm.nih.gov/pubmed/28552963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178198
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