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Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the [Formula: see text] statistic
Background: MR-Egger regression has recently been proposed as a method for Mendelian randomization (MR) analyses incorporating summary data estimates of causal effect from multiple individual variants, which is robust to invalid instruments. It can be used to test for directional pleiotropy and prov...
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| Опубликовано в: : | Int J Epidemiol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5446088/ https://ncbi.nlm.nih.gov/pubmed/27616674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyw220 |
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