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Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation
Chaperone-mediated autophagy (CMA), a selective form of protein lysosomal degradation, is maximally activated in stress situations to ensure maintenance of cellular homeostasis. CMA activity decreases with age and in several human chronic disorders, but in contrast, in most cancer cells, CMA is upre...
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| Publicado no: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5446085/ https://ncbi.nlm.nih.gov/pubmed/28410006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1293767 |
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