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Strategic incorporation of fluorine in the drug discovery of new-generation antitubercular agents targeting bacterial cell division protein FtsZ()

This article presents an account of our research on the discovery and development of new-generation fluorine-containing antibacterial agents against drug-resistant tuberculosis, targeting FtsZ. FtsZ is an essential protein for bacterial cell division and a highly promising therapeutic target for ant...

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Detalles Bibliográficos
Publicado en:J Fluor Chem
Autores principales: Ojima, Iwao, Awasthi, Divya, Wei, Longfei, Haranahalli, Krupanandan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445929/
https://ncbi.nlm.nih.gov/pubmed/28555087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2016.07.020
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