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Discovery of anti-TB agents that target the cell-division protein FtsZ

The emergence of multidrug-resistant Mycobacterium tuberculosis strains has made many of the currently available anti-tuberculosis (TB) drugs ineffective. Accordingly, there is a pressing need to identify new drug targets. Filamentous temperature-sensitive protein Z (FtsZ), a bacterial tubulin homol...

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Библиографические подробности
Главные авторы: Kumar, Kunal, Awasthi, Divya, Berger, William T, Tonge, Peter J, Slayden, Richard A, Ojima, Iwao
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039483/
https://ncbi.nlm.nih.gov/pubmed/21339840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.10.220
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