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PSE-HMM: genome-wide CNV detection from NGS data using an HMM with Position-Specific Emission probabilities
BACKGROUND: Copy Number Variation (CNV) is envisaged to be a major source of large structural variations in the human genome. In recent years, many studies apply Next Generation Sequencing (NGS) data for the CNV detection. However, still there is a necessity to invent more accurate computational too...
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| Publicat a: | BMC Bioinformatics |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5445519/ https://ncbi.nlm.nih.gov/pubmed/27809781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1296-y |
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