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PSE-HMM: genome-wide CNV detection from NGS data using an HMM with Position-Specific Emission probabilities

BACKGROUND: Copy Number Variation (CNV) is envisaged to be a major source of large structural variations in the human genome. In recent years, many studies apply Next Generation Sequencing (NGS) data for the CNV detection. However, still there is a necessity to invent more accurate computational too...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Malekpour, Seyed Amir, Pezeshk, Hamid, Sadeghi, Mehdi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445519/
https://ncbi.nlm.nih.gov/pubmed/27809781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1296-y
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